Chiral sulfinamide/achiral sulfonic acid cocatalyzed enantioselective protonation of enol silanes.
نویسندگان
چکیده
The application of chiral sulfinamides and achiral sulfonic acids as a cocatalyst system for enantioselective protonation reactions is described. Structurally simple, easily accessible sulfinamides were found to induce moderate-to-high ee's in the formation of 2-aryl-substituted cycloalkanones from the corresponding trimethylsilyl enol ethers.
منابع مشابه
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ورودعنوان ژورنال:
- Organic letters
دوره 13 16 شماره
صفحات -
تاریخ انتشار 2011